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Researchers use fruit fly to develop a novel disease model for Pitt-Hopkins syndrome – News-Medical.Net

The researchers from the TalTech molecular neurobiology laboratory headed by professor Tõnis Timmusk used the fruit fly, Drosophila melanogaster to develop a no…

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Reviewed by Emily Henderson, B.Sc.Sep 29 2020
The researchers from the TalTech molecular neurobiology laboratory headed by professor Tõnis Timmusk used the fruit fly, Drosophila melanogaster to develop a novel disease model for Pitt-Hopkins syndrome (PTHS). Their study was reported in the July issue of Disease Models and Mechanisms.
The PTHS syndrome is caused by mutations in one of the two copies of the TCF4 gene. PTHS patients suffer from moderate to severe intellectual disability: they typi…

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